Protective role of sphaeranthus amaranthoides on hepatic marker enzymes
: hepatic marker enzymes; sphaeranhtus amaranthodies; ethanol; D-galactosamine; hepato- toxicity; hepatoprotective activity; antioxidant activity
Abstract
The ethanolic extract of Sphaeranthus amaranthoides at an oral dosage 500mg/kg body weight exhibited a significant protection against D-galactosamine induced liver damage. Sphaeranthus amaranthoides showed hepatoprotective activity by reducing a D-galactosamine induced alteration in biochemical changes, that was evident by examination of the levels of hepatic marker enzymes. The plant extract may interfere with free radical formation or it may exert antioxidant activity which may result in hepatoprotective action.
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