Phyto-Melatonin and Immunity: A Review

Ghosh S

Authors

Ghosh S

cytokine, goat, immunity, melatonin, phytomelatonin, supplementation

Abstract

The basic structure of melatonin is evolutionarily conserved. Hence, it was speculated that melatonin may be present in different animals (from unicellular to multi-cellular) and even in plants. Melatonin in plans is generally regarded as phyto-melatonin. Like the role of melatonin in animals, phyto-melatonin can perform a number of functions like attenuation of apoptosis, prevention of free radical generation, protection against UV irradiation etc. But, unlike phytoestrogen, the role of phyto-melatonin in animals is totally an unexplored area. Hence, aim of the present study was to note the role of phyto-melatonin in maintenance of general health and immunity of goats. To fulfil the aim, we supplemented the goats with phyto-melatonin rich diet i.e. corn (Zea mays) which is having 1.4 ng/gm of dry weight of tissue and they are also edible to goats. We noted significantly high level of body weight, haematological (AST, ALT level, total RBC count and %Hb), immunological (TLC, %LC, %SR of PBMCs), metabolic (plasma glucose, cholesterol, HDL, LDL, protein levels and HDL: LDL ration), free radical (SOD, catalase, GPx levels), hormonal (estrogen, melatonin), cytokine (IL-6 and TNF-α) levels and significantly low level of MDA.

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How to Cite

Phyto-Melatonin and Immunity: A Review. (2021). Global Journal of Science Frontier Research, 21(C4), 23-30. https://www.journalofscience.org/index.php/GJSFR/article/view/3011

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