Active Fractions of Methanol Crude Obtained from Acacia Seyal Gum and their Antiproliferative Effects against Human Breast Cancer Cell Lines

Ahmed. A. M. Elnour; Mohamed E. S. Mirghani; N. A. Kabbashi; Djabir Daddiouaissa; Khalid Hamid Musa; Nour Hamid Abdurahman

Authors

Ahmed. A. M. Elnour
Mohamed E. S. Mirghani
N. A. Kabbashi
Djabir Daddiouaissa
Khalid Hamid Musa
Nour Hamid Abdurahman

cytotoxicity activity; acacia seyal gum; breast cancer(MCF-7); methanol extract/fraction, and GC-MS/MS

Abstract

Abstract not found

Downloads

How to Cite

Active Fractions of Methanol Crude Obtained from Acacia Seyal Gum and their Antiproliferative Effects against Human Breast Cancer Cell Lines. (2020). Global Journal of Science Frontier Research, 20(C3), 51-64. https://www.journalofscience.org/index.php/GJSFR/article/view/2719

Download Citation

References

Rebecca Siegel, Kimberly Miller, Ahmedin Jemal (2019) Cancer statistics, 2019. 69(1), 7-34.

Rebecca Siegel, Kimberly Miller, Ahmedin Jemal (2017) Cancer statistics, 2017. 67(1), 7-30.

M Stengler (2018) Outside the Box Cancer Therapies: Alternative Therapies That Treat and Prevent Cancer.

S Raguz, E Yagüe (2008) Resistance to chemotherapy: new treatments and novel insights into an old problem. 99(3), 387-391.

Ahmed Am Elnour, Mohamed Es Mirghani, Kabbashi Na, Md Alam Z, Khalid H Musa (2018) Study of Antioxidant and Anti-Inflammatory Crude Methanol Extract and Fractions of Acacia seyal Gum. 05(01), 3.

B Ali, I Al-Husseni, S Beegam, A Al-Shukaili, A Nemmar, S Schierling (2013) Effect of gum arabic on oxidative stress and inflammation in adenineinduced chronic renal failure in rats. 8, e55242.

D Glover, K Ushida, A Phillips, S Riley (2009) Acacia (sen) SUPERGUM™(Gum Arabic): an evaluation of potential health benefits in human subjects. 23, 2410-2415.

Raul Wapnir, Barbara Sherry, Champa Codipilly, Leslie Goodwin, Ivana Vancurova (2008) Modulation of Rat Intestinal Nuclear Factor NF-κB by Gum Arabic. 53(1), 80-87.

Ahmed. Elnour, Mohamed Mirghani, Nassereldin Kabbashi, Md. Alam, Khalid Musa (2018) GUM ARABIC: AN OPTIMIZATION OF ULTRASONIC- ASSISTED EXTRACTION OF ANTIOXIDANT ACTIVITY. 63, 95-116.

Sameera Samarakoon, Chanthirika Shanmuganathan, Meran Ediriweera, Kamani Tennekoon, Poorna Piyathilaka, Ira Thabrew, E Dilip De Silva (2016) In vitro Cytotoxic and Antioxidant Activity of Leaf Extracts of Mangrove Plant, Phoenix paludosa Roxb. 15(1), 127.

Vanicha Vichai, Kanyawim Kirtikara (2006) Sulforhodamine B colorimetric assay for cytotoxicity screening. 1(3), 1112-1116.

Khalid Musa, Aminah Abdullah, Khairiah Jusoh, Vimala Subramaniam (2011) Antioxidant Activity of Pink-Flesh Guava (Psidium guajava L.): Effect of Extraction Techniques and Solvents. 4(1), 100-107.

V Stankov, V Ili Ć M, Mitić, T Mihajilov -Krstev, S Simonović, S Mandić (2015) Secondary metabolites of Seseli rigidum: Chemical composition plus antioxidant, antimicrobial and cholinesterase inhibition activity. 111, 78-90.

G Fouche, G Cragg, P Pillay, N Kolesnikova, V Maharaj, J Senabe (2008) In vitro anticancer screening of South African plants. 119(3), 455-461.

John Manthey, Najla Guthrie (2002) Antiproliferative Activities of Citrus Flavonoids against Six Human Cancer Cell Lines. 50(21), 5837-5843.

M Boyd (1997) 2 The NCI in-vitro. Anticancer drug development guide: preclinical screening. 2, 23-42.

V Kuete, A Fankam, B Wiench, T Efferth (2013) Cytotoxicity and modes of action of the methanol extracts of six Cameroonian medicinal plants against multidrug-resistant tumor cells.

Khalil Rehman, Mark Wingertzahn, Saul Teichberg, Rita Harper, Raul Wapnir (2003) Gum Arabic (GA) Modifies Paracellular Water and Electrolyte Transport in the Small Intestine. 48(4), 755-760.

C Sanchez, M Nigen, V Mejia Tamayo, T Doco, P Williams, C Amine, D Renard (2018) Acacia gum: History of the future. 78, 140-160.

Giou-Teng Yiang, Pei-Lun Chou, Yu-Ting Hung, Jen-Ni Chen, Wei-Jung Chang, Yung-Luen Yu, Chyou-Wei Wei (2014) Vitamin C enhances anticancer activity in methotrexate-treated Hep3B hepatocellular carcinoma cells. 32(3), 1057-1063.

J Teng, A Pourmand, M Mazer-Amirshahi (2018) Vitamin C: The next step in sepsis management?. 43, 230-234.

X Huang, A Madan (1999) CAP3: A DNA sequence assembly program. 9, 868-877.

Bharat Aggarwal, Shishir Shishodia (2006) Molecular targets of dietary agents for prevention and therapy of cancer. 71(10), 1397-1421.

Garry Duthie, Susan Duthie, Janet Kyle (2000) Plant polyphenols in cancer and heart disease: implications as nutritional antioxidants. 13(1), 79-106.

W Davis, M Lamson, S Matthew, N Brignall (2000) Antioxidants and cancer III: Quercetin. 5, 196-208.

M Anderson, Jaz Jankowski (2003) The role of receptor tyrosine kinase inhibition in treating gastrointestinal malignancy. 12(4), 577-592.

K Brusselmans, R Vrolix, G Verhoeven, J Swinnen (2005) Induction of cancer cell apoptosis by flavonoids is associated with their ability to inhibit fatty acid synthase activity. 280, 5636-5645.

Koen Brusselmans, Ellen De Schrijver, Walter Heyns, Guido Verhoeven, Johannes Swinnen (2003) Epigallocatechin‐3‐gallate is a potent natural inhibitor of fatty acid synthase in intact cells and selectively induces apoptosis in prostate cancer cells. 106(6), 856-862.

Barry Markaverich, Rebecca Roberts, Mary Alejandro, Gregory Johnson, Brian Middleditch, James Clark (1988) Bioflavonoid interaction with rat uterine type ii binding sites and cell growth inhibition. 30(1-6), 71-78.

R Singhal, Y Yeh, N Prajda, E Olah, G Sledge, G Weber (1995) Quercetin down-regulates signal transduction in human breast carcinoma cells. 208, 425-431.

Charles Carraher, Michael Roner, Kimberly Shahi, Alisa Moric-Johnson, Lindsey Miller, Girish Barot, Amitabh Battin, Nancy Trang, Nandalall Sookdeo, Zamil Islam (2015) Control of Breast Cancer Using Organotin Polymers. 64(15), 800-814.

M-H Siess, Le Bon, A-M Canivenc-Lavier, M-C Amiot, M-J Sabatier, S, Aubert Sy (1996) Flavonoids of Honey and Propolis: Characterisation and Effects on Hepatic Drug-Metabolizing Enzymes and Benzo [a] pyrene -DNA Binding in Rats. 44, 2297-2301.

Amita Mishra, Shashank Kumar, Abhay Pandey (2013) Scientific Validation of the Medicinal Efficacy of Tinospora cordifolia. 2013(1).

Tomohiro Sawa, Mayumi Nakao, Takaaki Akaike, Kanji Ono, Hiroshi Maeda (1999) Alkylperoxyl Radical-Scavenging Activity of Various Flavonoids and Other Phenolic Compounds: Implications for the Anti-Tumor-Promoter Effect of Vegetables. 47(2), 397-402.

Zeba Siddiqui, Gulrana Khuwaja, M Asad (2006) One‐Pot Synthesis of 3‐Acetoacetyl‐5‐oxo‐5H‐[1]benzopyrano[3,2‐e]pyridin‐2‐one from Triacetic Acid Lactone.. 38(6).

Theodossis Theodossiou, Dimitris Tsiourvas, John Hothersall (2010) Hypericin Hydroquinone: Potential as a Red‐Far Red Photosensitizer?. 86(1), 18-22.

George Kraus, Kevin Basemann, Tezcan Guney (2015) Selective pyrone functionalization: reductive alkylation of triacetic acid lactone. 56(23), 3494-3496.

Philip Calder (2013) Omega‐3 polyunsaturated fatty acids and inflammatory processes: nutrition or pharmacology?. 75(3), 645-662.

Anna Bogucka-Kocka, Christian Zidorn, Małgorzata Kasprzycka, Grażyna Szymczak, Katarzyna Szewczyk (2016) Phenolic acid content, antioxidant and cytotoxic activities of four Kalanchoë species. 25(4), 622-630.

U Gawlik-Dziki, D Dziki, M Świeca, R Nowak (2017) Mechanism of action and interactions between xanthine oxidase inhibitors derived from natural sources of chlorogenic and ferulic acids. 225, 138-145.

W Li, N Li, Y Tang, B Li, L Liu, X Zhang (2012) Biological activity evaluation and structure-activity relationships analysis of ferulic acid and caffeic acid derivatives for anticancer. 22, 6085-6088.

Sandrina Heleno, Anabela Martins, Maria Queiroz, Isabel Ferreira (2015) Bioactivity of phenolic acids: Metabolites versus parent compounds: A review. 173, 501-513.

N Dubost, B Ou, R Beelman (2007) Quantification of polyphenols and ergothioneine in cultivated mushrooms and correlation to total antioxidant capacity. 105(2), 727-735.

Suphat Phongthai, Stefano D'amico, Regine Schoenlechner, Wantida Homthawornchoo, Saroat Rawdkuen (2018) Fractionation and antioxidant properties of rice bran protein hydrolysates stimulated by in vitro gastrointestinal digestion. 240, 156-164.

M Mirghani, A Elnour, N Kabbashi, M Alam, K Musa, A Abdullah (2018) Determination of antioxidant activity of gum arabic: An exudation from two different locations. 44, 179-186.

M Mirghania, A Elnour, N Kabbashia, M Alama, K Musa, A Abdullah (2018) Determination of antioxidant activity of gum arabic: An exudation from two different locations. 44, 179-186.

Ahmed Elnour, Mohamed Mirghani, Nassereldeen Kabbashi, Md Alam, Khalid Musa (2017) Active Fractions of Methanol Crude Obtained from Acacia seyal gum: Antioxidant Capacity, using FTIR Analysis. 2(2), 94-107.